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Experimental and numerical study of stenotic flows


Abdul Khader, Shah Mohammed and Adathala, Rajeev and Ayachit, Anurag and Pai, Raghuvir and Vayalappil, Muraleedharan C. and Zuber, Mohammad and Rao, V. R. K. (2016) Experimental and numerical study of stenotic flows. Journal of Medical Imaging and Health Informatics, 6 (6). pp. 1500-1506. ISSN 2156-7018; ESSN: 2156-7026


Atherosclerosis has been leading cause of deaths in several countries. Recent technical advances have allowed the investigation of stenotic flows and in understanding the implications with increased severity. Such studies shall provide detailed understanding of flow across stenosis and its progression. In the present study, a large artery representing segment of aorta is considered as test specimen. Experimental study is carried out by generating the pulsatile flow through pulsatile duplicator. Flow across normal and various severities of stenosis such as 25%, 50% and 75% are studied. Numerical simulation using CFD is also carried out in similar normal and stenosed models. A novel concept of using pulse duplicator to generate pulsatile waves and investigate the different stenosed models has been adopted. Results obtained experimentally and numerically are compared and agree well with that of clinical observations. This study demonstrates significant variation of haemodynamic in post-stenotic region with increased stenosis. Increased pulse pressure, phase lag is observed with increased severity. It is also observed that stenosis greater than 75% is significant as flow complexity is induced with considerable disturbance even in early and latter part of pulse cycle. Such study shall be useful in understanding the flow changes in stenosis and enhance clinical observation.

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Additional Metadata

Item Type: Article
Subject: Arterial stenosis; CFD; Haemodynamic; Stenotic flow
Divisions: Faculty of Engineering
DOI Number: https://doi.org/10.1166/jmihi.2016.1838
Publisher: American Scientific Publishers
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 08 Mar 2018 02:35
Last Modified: 08 Mar 2018 02:35
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1166/jmihi.2016.1838
URI: http://psasir.upm.edu.my/id/eprint/54231
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