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Prevalence of leptospirosis in healthy dogs and dogs with kidney disease in Klang Valley, Malaysia


Citation

Lau, Seng Fong and Low, Kae Neng and Khor, Kuan Hua and Roslan, Mohd Azri and Bejo, Siti Khairani and Radzi, Rozanaliza and Bahaman, Abdul Rani (2016) Prevalence of leptospirosis in healthy dogs and dogs with kidney disease in Klang Valley, Malaysia. Tropical Biomedicine, 33 (3). pp. 469-475. ISSN 0127-5720

Abstract

Leptospirosis is under-reported and remarkably neglected in Malaysia, especially in companion animals. In recent years, dogs have become popular pets and potentially act as one of the risk factors for human leptospiral infection. The purpose of this study was to determine the serological and molecular status of leptospirosis in healthy and dogs with kidney disease in Klang Valley, Malaysia and to gain insight of the possible serovars involved in the dog population in Klang Valley, Malaysia. Blood samples were obtained from 57 dogs (19 kidney disease patient; 38 healthy dogs, respectively). Serum samples obtained from these animals were screened for leptospiral antibodies by the microscopic agglutination test (MAT). Polymerase chain reaction (PCR) assay was performed on plasma samples to detect leptospiral DNA. By MAT, three out of 19 (15.8%) dogs with kidney disease were positive for L. canicola. One out of 38 (2.6%) healthy dogs was positive for L. icterohemorrhagiae. The overall seroprevalence for leptospirosis in dogs in Klang Valley, Malaysia was 7.0% (n=4/57). Only one out of the 19 dogs (5.3%) with kidney disease was tested positive to pathogenic Leptospira by PCR assay. All the 38 healthy dogs were negative. Positive results in healthy dogs and dogs with kidney disease for leptospirosis warrant further investigation of leptospirosis in dog population in Malaysia. The prevalence and incidence of this disease in the dog population in this country need further investigation.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Veterinary Medicine
Publisher: Malaysian Society of Parasitology and Tropical Medicine
Keywords: Leptospirosis; Healthy dog; Dog; Kidney disease; Klang valley; Malaysia
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 04 Jan 2018 02:24
Last Modified: 04 Jan 2018 02:24
URI: http://psasir.upm.edu.my/id/eprint/53664
Statistic Details: View Download Statistic

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