Citation
Tong, Chih Kong and Vidyadaran, Sharmili
(2016)
Role of microglia in embryonic neurogenesis.
Experimental Biology and Medicine, 241 (15).
pp. 1669-1675.
ISSN 1535-3702; ESSN: 1535-3699
Abstract
Microglia begin colonizing the developing brain as early as embryonic day 9, prior to the emergence of neurons and other glia. Their ontogeny is also distinct from other central nervous system cells, as they derive from yolk sac hematopoietic progenitors and not neural progenitors. In this review, we feature these unique characteristics of microglia and assess the spatiotemporal similarities between microglia colonization of the central nervous system and embryonic neurogenesis. We also infer to existing evidence for microglia function from embryonic through to postnatal neurodevelopment to postulate roles for microglia in neurogenesis.
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Official URL or Download Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC49954...
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Medicine and Health Science |
| DOI Number: | https://doi.org/10.1177/1535370216664430 |
| Publisher: | Sage Publications |
| Keywords: | Microglia; Embryonic neurogenesis; Neurodevelopment |
| Depositing User: | Ms. Ainur Aqidah Hamzah |
| Date Deposited: | 16 Mar 2022 08:33 |
| Last Modified: | 16 Mar 2022 08:33 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1177/1535370216664430 |
| URI: | http://psasir.upm.edu.my/id/eprint/52912 |
| Statistic Details: | View Download Statistic |
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