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Validation of a modified algometer to measure nociceptive thresholds in awake dogs


Citation

Kaka, Ubedullah and Hui, Cheng Chen and Yong, Meng Goh and Abdul Abubakar, Adamu and Fakurazi, Sharida and Ebrahimi, Mahdi (2015) Validation of a modified algometer to measure nociceptive thresholds in awake dogs. BioMed Research International. art. no. 375421. pp. 1-7. ISSN 2314-6133; ESSN: 2314-6141

Abstract

This study was conducted to validate the use of a modified algometer device to measure mechanical nociceptive thresholds in six dogs. Dogs were administered morphine intravenously (IV) at 1 mg/kg or saline at equivolume in a crossover design with one-week washout period. Mechanical nociceptive thresholds were determined before, after the administration of treatments at 5 minutes, and hourly for 8 hours. Thresholds were recorded at the carpal pad, metacarpal foot pad, tibia, femur, and abdomen. Heart rates, body temperature, and respiration were recorded at similar time points. Thresholds increased significantly (


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Faculty of Veterinary Medicine
Institute of Bioscience
DOI Number: https://doi.org/10.1155/2015/375421
Publisher: Hindawi Publishing Corporation
Keywords: Algometer; Mechanical nociceptive
Depositing User: Ms. Nida Hidayati Ghazali
Date Deposited: 31 Jan 2018 06:57
Last Modified: 31 Jan 2018 06:57
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2015/375421
URI: http://psasir.upm.edu.my/id/eprint/46847
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