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The first Malay database toward the ethnic-specific target molecular variation


Citation

Fikri, Hashim Halim and Etemad, Ali and Abdul Latif, Ahmad Zubaidi and Merican, Amir Feisal and Baig, Atif Amin and Annuar, Azlina Ahmad and Ismail, Endom and Salahshourifar, Iman and Liza Sharmini, Ahmad Tajudin and Ramli, Marini and Shah, Mohamed Irwan and Johan, Muhammad Farid and Nik Hassan, Nik Norliza and Abdul Aziz, Noraishah Mydin and Mohd Noor, Noor Haslina and Ab Rajab, Nur Shafawati and Hassan, Rosline and Bahar, Rosnah and Zain, Rosnah and Mohamed Yusoff, Shafini and Yusoff, Surini and Soon, Guan Tan and Meow, Keong Thong and Wan Isa, Hatin and Abdullah, Wan Zaidah and Mohamed, Zahurin and Abdul Latiff, Zarina and Zilfalil, Alwi (2015) The first Malay database toward the ethnic-specific target molecular variation. BMC Research Notes, 8 (176). pp. 1-6. ISSN 1756-0500

Abstract

BACKGROUND:The Malaysian Node of the Human Variome Project (MyHVP) is one of the eighteen official Human Variome Project (HVP) country-specific nodes. Since its inception in 9(th) October 2010, MyHVP has attracted the significant number of Malaysian clinicians and researchers to participate and contribute their data to this project. MyHVP also act as the center of coordination for genotypic and phenotypic variation studies of the Malaysian population. A specialized database was developed to store and manage the data based on genetic variations which also associated with health and disease of Malaysian ethnic groups. This ethnic-specific database is called the Malaysian Node of the Human Variome Project database (MyHVPDb). FINDINGS:Currently, MyHVPDb provides only information about the genetic variations and mutations found in the Malays. In the near future, it will expand for the other Malaysian ethnics as well. The data sets are specified based on diseases or genetic mutation types which have three main subcategories: Single Nucleotide Polymorphism (SNP), Copy Number Variation (CNV) followed by the mutations which code for the common diseases among Malaysians. MyHVPDb has been open to the local researchers, academicians and students through the registration at the portal of MyHVP ( http://hvpmalaysia.kk.usm.my/mhgvc/index.php?id=register ). CONCLUSIONS:This database would be useful for clinicians and researchers who are interested in doing a study on genomics population and genetic diseases in order to obtain up-to-date and accurate information regarding the population-specific variations and also useful for those in countries with similar ethnic background.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
DOI Number: https://doi.org/10.1186/s13104-015-1123-y
Publisher: BioMed Central
Keywords: Malaysian node of the human variome project; Ethnic-specific molecular variation database; SNPs; CNVs; Disease genes and their products
Depositing User: Nida Hidayati Ghazali
Date Deposited: 20 Mar 2018 04:39
Last Modified: 20 Mar 2018 04:39
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1186/s13104-015-1123-y
URI: http://psasir.upm.edu.my/id/eprint/46597
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