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Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines


Citation

Ting, T. T. C. and Crouse, K. A. and Ahmad, H. (2015) Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines. Sains Malaysiana, 44 (4). pp. 619-628. ISSN 0026-6039

Abstract

Three novel ruthenium(II) complexes of the general formula [Ru(II)(bpy)2L]2+ were synthesized, where L = 1,10-phenanthroline derivatives of position 2 imidazole having 3,4-didecyloxy-phenyl (ddip), 3,4-ditetradecyloxy-phenyl (dtip) and 3,4-dihexadecyloxy-phenyl (dhip). All complexes were characterized by elemental analysis, 1H-NMR and ESI-MS. Their photophysical properties have also been studied by UV-visible spectroscopy and fluorescence spectroscopy. The complexes exhibit Ru(II) metal centered emission at approximately 610 nm in acetonitrile solution at room temperature. DNA binding studies were carried out by UV-visible titration, luminescence titration and viscosity studies. The results indicated that [Ru(bpy)2(ddip)]2+ binds to CT-DNA by partial intercalation mode, while [Ru(bpy)2(dtip)]2+ and [Ru(bpy)2(dhip)]2+ bind intercalatively via extended ligands.


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Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines.pdf

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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
DOI Number: https://doi.org/10.17576/jsm-2015-4404-18
Publisher: Universiti Kebangsaan Malaysia
Keywords: DNA binding; Polypyridyl ligand; Ruthenium(II) complex; Transition metal complexes
Depositing User: Nida Hidayati Ghazali
Date Deposited: 27 Feb 2018 03:34
Last Modified: 27 Feb 2018 03:34
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.17576/jsm-2015-4404-18
URI: http://psasir.upm.edu.my/id/eprint/46480
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