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Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus


Citation

Shariff Ghazali, Sazlina and Ismail, Mastura and Cheong, Ai Theng and Bujang, Mohamad Adam and Haniff, Jamaiyah and Lee, Ping Yein and Syed Abdul Rahman, Syed Alwi and Chew, Boon How (2015) Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus. Singapore Medical Journal, 56 (5). pp. 284-290. ISSN 0037-5675

Abstract

Introduction:We assessed the predictors of poor glycaemic control among older patients with type 2 diabetes mellitus (T2DM) in Malaysia. Methods:This cross-sectional study used the data of 21,336 patients aged ≥ 60 years with T2DM from the Adult Diabetes Control and Management Registry 2008-2009. Results:Predictors of poor glycaemic control were: age groups 60-69 years (odds ratio [OR] 1.96, 95% confidence interval [CI] 1.66-2.33) and 70-79 years (OR 1.43, 95% CI 1.20-1.71); Malay (OR 1.53, 95% CI 1.41-1.66) and Indian (OR 1.32, 95% CI 1.19-1.46) ethnicities; T2DM durations of 5-10 years (OR 1.46, 95% CI 1.35-1.58) and > 10 years (OR 1.75, 95% CI 1.59-1.91); the use of oral antidiabetic agents only (OR 5.86, 95% CI 3.32-10.34), insulin only (OR 17.93, 95% CI 9.91-32.43), and oral antidiabetic agents and insulin (OR 29.42, 95% CI 16.47-52.53); and elevated blood pressure (OR 1.10, 95% CI 1.01-1.20), low-density lipoprotein cholesterol (OR 1.48, 95% CI 1.38-1.59) and triglycerides (OR 1.61, 95% CI 1.51-1.73). Hypertension (OR 0.71, 95% CI 0.64-0.80), hypertension and dyslipidaemia (OR 0.68, 95% CI 0.61-0.75), pre-obesity (OR 0.89, 95% CI 0.82-0.98) and obesity (OR 0.76, 95% CI 0.70-0.84) were less likely to be associated with poor glycaemic control. Conclusion:Young-old and middle-old age groups (i.e. < 80 years), Malay and Indian ethnicities, longer T2DM duration, the use of pharmacological agents, and elevated blood pressure and lipid levels were associated with poor glycaemic control. The presence of comorbidities, pre-obesity and obesity were less likely to be associated with poor glycaemic control.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Institute of Gerontology
DOI Number: https://doi.org/10.11622/smedj.2015055
Publisher: Singapore Medical Association
Keywords: Diabetes mellitus; Glycaemic control; Malaysia; Older patients; Registry
Depositing User: Ms. Nida Hidayati Ghazali
Date Deposited: 15 May 2018 02:28
Last Modified: 25 Nov 2019 08:26
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.11622/smedj.2015055
URI: http://psasir.upm.edu.my/id/eprint/45941
Statistic Details: View Download Statistic

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