Citation
Nahta, Rita and Al-Mulla, Fahd and Al-Temaimi, Rabeah and Amedei, Amedeo and Andrade Vieira, Rafaela and Bay, Sarah N. and Brown, Dustin G. and Calaf, Gloria M. and Castellino, Robert C. and Cohen Solal, Karine A. and Colacci, Anna Maria and Cruickshanks, Nichola and Dent, Paul and Di Fiore, Riccardo and Forte, Stefano and Goldberg, Gary S. and A. Hamid, Roslida and Krishnan, Harini and Laird, Dale W. and Lasfar, Ahmed and Marignani, Paola A. and Memeo, Lorenzo and Mondello, Chiara and Naus, Christian C. and Ponce Cusi, Richard and Raju, Jayadev and Roy, Debasish and Roy, Rabindra and Ryan, Elizabeth P. and Salem, Hosni K. and Scovassi, A. Ivana and Singh, Neetu and Vaccari, Monica and Vento, Renza and Vondrá ček, Jan and Wade, Mark and Woodrick, Jordan and Bisson, William H.
(2015)
Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.
Carcinogenesis, 36 (suppl. 1).
pp. 2-18.
ISSN 0143-3334; ESSN: 1460-2180
Abstract
As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks.
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Official URL or Download Paper: https://pubmed.ncbi.nlm.nih.gov/26106139/
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Medicine and Health Science |
| DOI Number: | https://doi.org/10.1093/carcin/bgv028 |
| Publisher: | Oxford University Press |
| Keywords: | Cellular; Cancer; Cell; DNA |
| Depositing User: | Ms. Nuraida Ibrahim |
| Date Deposited: | 06 May 2021 23:28 |
| Last Modified: | 06 May 2021 23:28 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1093/carcin/bgv028 |
| URI: | http://psasir.upm.edu.my/id/eprint/45440 |
| Statistic Details: | View Download Statistic |
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