Citation
Ling, King Hwa and Brautigan, Peter J. and Moore, Sarah and Fraser, Rachel and Leong, Melody Pui Yee and Leong, Jia Wen and Zainal Abidin, Shahidee and Lee, Han Chung and Cheah, Pike See and Raison, Joy M. and Babic, Milena and Lee, Young Kyung and Daish, Tasman and Mattiske, Deidre M. and Mann, Jeffrey R. and Adelson, David L. and Thomas, Paul Q. and Hahn, Christopher N. and Scott, Hamish S.
(2016)
In depth analysis of the Sox4 gene locus that consists of sense and natural antisense transcripts.
Data in Brief, 7.
pp. 282-290.
ISSN 2352-3409
Abstract
SRY (Sex Determining Region Y)-Box 4 or Sox4 is an important regulator of the pan-neuronal gene expression during post-mitotic cell differentiation within the mammalian brain. Sox4 gene locus has been previously characterized with multiple sense and overlapping natural antisense transcripts [1] and [2]. Here we provide accompanying data on various analyses performed and described in Ling et al. [2]. The data include a detail description of various features found at Sox4 gene locus, additional experimental data derived from RNA-Fluorescence in situ Hybridization (RNA-FISH), Western blotting, strand-specific reverse-transcription quantitative polymerase chain reaction (RT-qPCR), gain-of-function and in situ hybridization (ISH) experiments. All the additional data provided here support the existence of an endogenous small interfering- or PIWI interacting-like small RNA known as Sox4_sir3, which origin was found within the overlapping region consisting of a sense and a natural antisense transcript known as Sox4ot1.
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