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Expectant management of missed miscarriage


Andi Asri, Andi Anggeriana and Mat Adenan, Noor Azmi and Esfehani, Ali Jafarzadeh and Mohtaruddin, Nurhafizah and Ma, Saung Oo and A. Latiff, Latiffah (2015) Expectant management of missed miscarriage. Malaysian Journal of Medicine and Health Sciences, 11 (1). pp. 69-76. ISSN 1675-8544

Abstract / Synopsis

Early pregnancy losses occur in 10-20% of all pregnancies. Surgical evacuation has always been the mainstay of management of miscarriages. The main aim of this study was to understand the success rate of expectant management of miscarriage with regards to gestational sac size and period of gestation. The secondary outcome was to measure the satisfaction level and the rate of pregnancy after 6 month of expectant management. Patients diagnosed with missed miscarriages were requested to choose between expectant or surgical management. Those decided for expectant management on “wait and watch” approach were assessed weekly up to 5 completed weeks until complete miscarriage was achieved spontaneously. Surgical evacuation was performed if medically indicated or requested by the patients at any time or at the end of fifth week if complete miscarriage was not achieved. Out of 212 cases, 75 (35.4%) opted for expectant management. Complete miscarriage was achieved in 85.3% of subjects by the end of fifth weeks respectively. Mean of Gestational sac size and period of gestation was not found to influence the success rate of complete spontaneous miscarriage in the expectant management. No morbidity was recorded during the five weeks of the study period. Mean satisfaction score was 9.7±8.3. Pregnancy occurred in 47% of patients within 6 months follow up. The Receiver operation characteristic (ROC) curve analysis suggested the end of second week as the cut off for surgical intervention. This study revealed that expectant management of missed miscarriage is a reliable management of missed miscarriage within the first two weeks.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Keywords: Expectant missed miscarriage; Safety; Management
Depositing User: Mohd Hafiz Che Mahasan
Date Deposited: 18 Dec 2015 05:52
Last Modified: 18 Dec 2015 05:52
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