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Alkaloids from Piper nigrum and Piper betle


Citation

Lim, Chyi Meei and Ee, Gwendoline Cheng Lian and Rahmani, Mawardi and Bong, Choon Fah Joseph (2009) Alkaloids from Piper nigrum and Piper betle. Pertanika Journal of Science & Technology, 17 (1). pp. 149-154. ISSN 0128-7680; ESSN: 2231-8526

Abstract / Synopsis

An investigation, on the roots of Piper nigrum and the aerial parts of Piper betle, has yielded several alkaloids. The dried root sample of Piper nigrum was extracted using various solvents in increasing polarity. The dried aerial part of Piper betle was extracted using the Soxhlet extraction method. The alkaloids isolated were pellitorine(1), (E)-1-[3',4'- (Methylenedioxy)cinnamoyl]piperidine(2), piperine(3), piperolactam D(4), cepharadione A(5), and 2,4-tetradecadienoic acid isobutyl amide(6). These compounds were isolated using chromatographic methods, while the elucidation of the structures was carried out using MS, IR and NMR techniques. The extracts of Piper nigrum and Piper betle were also tested for cytotoxicity activities. This is the first report on (E)-1-[3',4'-(Methylenedioxy)cinnamoyl] piperidine(2) from Piper nigrum as a natural product.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture and Food Sciences
Faculty of Science
Publisher: Universiti Putra Malaysia Press
Keywords: Piper nigrum; Piper betle; Alkaloids; Cytotoxicity
Depositing User: Noor Syafini Zamani
Date Deposited: 20 Nov 2015 11:58
Last Modified: 20 Nov 2015 11:58
URI: http://psasir.upm.edu.my/id/eprint/40551
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