Simple Search:

Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (ulam)


Citation

Mohamed Mackeen, Muhammad Mukram and Ali, Abdul Manaf and El-Sharkawy, Saleh Hassan and Abd Manap, Mohd Yazid and Mohd Salleh, Khalijah and Lajis, Nordin and Kawazu, Kazuyoshi (1997) Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (ulam). International Journal of Pharmacognosy, 35 (3). pp. 174-178. ISSN 1388-0209; ESSN: 1744-5116

Abstract / Synopsis

Ethanol extracts of 19 Malaysian traditional vegetables (locally known as ‘ulam’) belonging to 15 families were screened for antimicrobial and cytotoxic activities. Both the disc diffusion (qualitative) and tube dilution (quantitative) assays were employed for the determination of antimicrobial activity against six pathogenic microorganisms, i.e. two Gram-positive bacteria (Bacillus cereus and Bacillus megaterium), two Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and two fungi (Aspergillus ochraceous and Cryptococcus neoformans). Six extracts, i.e. Anacardium occidentale, Garcinia atroviridis, Averrhoa bilimbi, Polygonum minus, Diplazium esculentum and Etlingera elatior, showed antimicrobial with minimum inhibitory concentration (MIC) and minimum lethal concentration (MLC) values in the respective ranges of 100 ? 800 µg/ml and 400 ? 800 µg/ml. Seven extracts, i.e. Anacardium occidentale, Garcinia atroviridis, Sesbania grandiflora, Barringtonia racemosa, Polygonum minus, Kaempferia galanga and Etlingera elatior displayed cytotoxic activity against the HeLa (human cervical carcinoma) cell line with CD 50 values in the range of 10–30 µg/ml. The ‘ulam’ show potential as ‘functional food’ in view of the significant therapeutic and nutritive benefits.


Download File

[img]
Preview
PDF (Abstract)
Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (ulam).pdf

Download (50kB) | Preview

Additional Metadata

Item Type: Article
Divisions: Universiti Pertanian Malaysia
DOI Number: https://doi.org/10.1076/phbi.35.3.174.13294
Publisher: Swets & Zeitlinger
Keywords: 'Ulam'; Antimicrobial activity; Cytotoxic activity; Ethanol extracts; Functional food; Malaysian traditional vegetables
Depositing User: Nabilah Mustapa
Date Deposited: 18 Sep 2015 11:06
Last Modified: 18 Sep 2015 11:06
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1076/phbi.35.3.174.13294
URI: http://psasir.upm.edu.my/id/eprint/40436
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item