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Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review


Bagalkotkar, Gururaj and Sagineedu, Sreenivasa Rao and Saad, Mohd Said and Stanslas, Johnson (2006) Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review. Journal of Pharmacy and Pharmacology, 58 (12). pp. 1559-1570. ISSN 0022-3573; ESSN: 2042-7158


This review discusses the medicinal plant Phyllanthus niruri Linn. (Euphorbiaceae), its wide variety of phytochemicals and their pharmacological properties. The active phytochemicals, flavonoids, alkaloids, terpenoids, lignans, polyphenols, tannins, coumarins and saponins, have been identified from various parts of P. niruri. Extracts of this herb have been proven to have therapeutic effects in many clinical studies. Some of the most intriguing therapeutic properties include anti-hepatotoxic, anti-lithic, anti-hypertensive, anti-HIV and anti-hepatitis B. Therefore, studies relating to chemical characteristics and structural properties of the bioactive phytochemicals found in P. niruri are very useful for further research on this plant as many of the phytochemicals have shown preclinical therapeutic efficacies for a wide range of human diseases, including HIV/AIDS and hepatitis B.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture
Faculty of Medicine and Health Science
Institute of Bioscience
DOI Number: https://doi.org/10.1211/jpp.58.12.0001
Publisher: Royal Pharmaceutical Society of Great Britain
Keywords: Phyllanthus niruri Linn.; Phytochemicals; Pharmacological
Depositing User: Nabilah Mustapa
Date Deposited: 17 Sep 2015 01:40
Last Modified: 17 Sep 2015 01:40
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1211/jpp.58.12.0001
URI: http://psasir.upm.edu.my/id/eprint/40325
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