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Adverse effects of imidocarb dipropionate (Imizol®) in a dog


Abdullah, Abdul Salam and Abdul Rahman, Sheikh Omar and Baggot, J. Desmond and Zamri, M. (1984) Adverse effects of imidocarb dipropionate (Imizol®) in a dog. Veterinary Research Communications, 8 (1). pp. 55-59. ISSN 0165-7380; ESSN: 1573-7446


One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haemorrhage in the cortex and medulla. Marked tubulonephrosis was also exhibited microscopically. Liver and spleen were moderately enlarged and congested. The adverse effects of imidocarb may be due to excessive acetylcholine action.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Veterinary Medicine
Universiti Pertanian Malaysia
DOI Number: https://doi.org/10.1007/BF02214695
Publisher: Springer
Keywords: Dogs; Imidocarb
Depositing User: Mohd Hafiz Che Mahasan
Date Deposited: 10 Aug 2015 02:51
Last Modified: 10 Aug 2015 02:51
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1007/BF02214695
URI: http://psasir.upm.edu.my/id/eprint/39503
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