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Mutagenic properties of modified hydrothermal nanotitania extract


Citation

Harun, Ahmad Mukifza and Ab. Ghani, Noor Baizura and Mohd Noor, Nor Farid and Abas @ Buang, Razif and Alam, Mohammad Khursheed (2020) Mutagenic properties of modified hydrothermal nanotitania extract. Bangladesh Journal of Medical Science, 19 (1). pp. 159-162. ISSN 2223-4721; ESSN: 2076-0299

Abstract

Backgrounds: The mutagenic properties of modified hydrothermal nanotitania extract were carried out using the Ames test (genotoxicity). Materials and methods: The Ames test was performed on Salmonella strains (TA98, TA100, TA1535, TA1537 and TA 102) which contain mutations in several genes with and without S9 metabolic activation from rat liver using the standard assay. The materials were extracted in distilled water and the serial dilutions of concentration ranging from 313 to 5000 μg/mL were used after the incubation period of 24 h at 37° C. Results: These results suggested that all tested concentrations of the material extracts did not produce mutagenic effect in all the strains tested. Conclusions: Findings from this study showed that the modified hydrothermal nanotitania extract was non-mutagenic under present conditions.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.3329/bjms.v19i1.43890
Publisher: Ibn Sina Medical College
Keywords: Mutagenicity; Ames test; Genotoxicity
Depositing User: Nabilah Mustapa
Date Deposited: 14 Apr 2020 13:58
Last Modified: 14 Apr 2020 13:58
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3329/bjms.v19i1.43890
URI: http://psasir.upm.edu.my/id/eprint/38103
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