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Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study


Mahmud, Mohd Hafizi and Nordin, Abdul Jalil and Ahmad Saad, Fathinul Fikri and Azman, Ahmad Zaid Fattah (2014) Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study. Journal of Physics: Conference Series, 546. art. no. 012008. pp. 1-6. ISSN 1742-6588; ESSN: 1742-6596


This study aims to estimate the radiation effective dose resulting from whole body fluorine-18 flourodeoxyglucose Positron Emission Tomography (18F-FDG PET) scanning as compared to conservative Computed Tomography (CT) techniques in evaluating oncology patients. We reviewed 19 oncology patients who underwent 18F-FDG PET/CT at our centre for cancer staging. Internal and external doses were estimated using radioactivity of injected FDG and volume CT Dose Index (CTDIvol), respectively with employment of the published and modified dose coefficients. The median differences of dose among the conservative CT and PET protocols were determined using Kruskal Wallis test with p < 0.05 considered as significant. The median (interquartile range, IQR) effective doses of non-contrasted CT, contrasted CT and PET scanning protocols were 7.50 (9.35) mSv, 9.76 (3.67) mSv and 6.30 (1.20) mSv, respectively, resulting in the total dose of 21.46 (8.58) mSv. Statistically significant difference was observed in the median effective dose between the three protocols (p < 0.01). The effective doses of whole body 18F-FDG PET technique may be effective the lowest amongst the conventional CT imaging techniques.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1088/1742-6596/546/1/012008
Publisher: IOP Publishing
Keywords: Radiation dose; 18 flourodeoxyglucose Positron Emission Tomography (18F-FDG PET); Computed Tomography (CT)
Depositing User: Nabilah Mustapa
Date Deposited: 16 Dec 2015 08:39
Last Modified: 16 Dec 2015 08:39
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1088/1742-6596/546/1/012008
URI: http://psasir.upm.edu.my/id/eprint/37499
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