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Environmental risk assessment for veterinary antibiotics and hormone in Malaysian agricultural soil


Ho, Yu Bin and Zakaria, Mohamad Pauzi and Abdul Latif, Puziah and Saari, Nazamid (2014) Environmental risk assessment for veterinary antibiotics and hormone in Malaysian agricultural soil. Iranian Journal of Public Health, 43 (suppl.3). pp. 67-71. ISSN 2251-6085; ESSN: 2251-6093


Background: Repeated applications of animal manure as fertilizer are normal agricultural practices in Malaysia that may release veterinary antibiotics to environment from treated animals. Methods: Environmental risk assessment (ERA) on 5 commonly used antibiotics and one hormone in Malaysian broiler farm was calculated using the ratio of measured environmental concentration (MEC) and predicted no effect concentration (PNEC) in the environment. PNEC was derived from the available acute and chronic toxicity data in the open peer-reviewed literature. Risk quotients (RQ) were then calculated for 5 antibiotics (erythromycin, norfloxacin, sulfadiazine, trimethoprim, and tylosin) and one hormone (progesterone). Results: RQ for tylosin has exceeded 1, indicating that this compound has high risk of acute toxicity in Malaysian agricultural soil while trimethoprim and tylosin possessed medium risk of chronic toxicity. The rest of the compounds showed low risk or no risk in acute or chronic ecological toxicity. Conclusion: The release of tylosin, trimethoprim, norfloxacin and progesterone from broiler manure to agricultural soil may potentially harm the environment.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Environmental Studies
Faculty of Food Science and Technology
Faculty of Medicine and Health Science
Publisher: Tehran University of Medical Sciences
Keywords: Veterinary antibiotic; Environmental risk assessment; Risk quotient; Malaysia
Depositing User: Nabilah Mustapa
Date Deposited: 16 Dec 2015 08:31
Last Modified: 16 Dec 2015 08:31
URI: http://psasir.upm.edu.my/id/eprint/37480
Statistic Details: View Download Statistic

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