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Detoxification related genes in gut of Coptotermes curvignathus


Charles, Suliana and King, Patricia Jie Hung and Bong, Joseph Choon Fah and Ong, Kian Huat and Abu Bakar, Farah Diba and Abdul Murad, Abdul Munir and Tsang, Adrian and Mahadi, Nor Muhammad (2014) Detoxification related genes in gut of Coptotermes curvignathus. Entomology, Ornithology & Herpetology, 3 (1). art. no. 117. pp. 1-2. ISSN 2161-0983


Coptotermes curvignathus (C. curvignathus) are subterranean termites that feed on living-tree as their sole diet,which consist mainly of cellulose, hemicelluloses, lignin, plant allele chemical and other environmental residues such as insecticide. The xenobiotic compounds, plant allele chemical and insecticide are hazardous to termites health and need to be transported out of their body via xenobiotic and detoxification metabolism. This paper highlighted the potential enzymes that play vital role in the xenobiotic and detoxification metabolism. Transcriptomic data were generated from 200 termite’s digestive system using Illumina HiSeq 2000. Raw data was trimmed and assembled by SOLEXAQA and Bowtie before loaded into Gene Ontology based data mining software, Blast2GO (B2G). The result showed that, C. curvignathus contain enzymes that involved in all three biotransformation phases of xenobiotic and detoxification metabolism, which included cytochrome P450s monooxygenases, glutathione S-transferase, carboxylesterase, UDPglucuronyltransferases and N-acetyltransferase. The result of this study is the first insight into Cc xenobiotic pathway.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture and Food Sciences
Publisher: Omics Publishing Group
Keywords: Coptotermes curvignathus; Xenobiotic; Detoxification; Cytochrome P450; Glutathione S-transferase
Depositing User: Nabilah Mustapa
Date Deposited: 21 Aug 2015 12:49
Last Modified: 07 Sep 2015 06:52
URI: http://psasir.upm.edu.my/id/eprint/37041
Statistic Details: View Download Statistic

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