Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root

Citation

Sowndhararajan, Kandhasamy and Chin, Nyuk Ling (2014) Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root. Agriculture and Agricultural Science Procedia, 2. pp. 406-414. ISSN 2210-7843

Abstract

The present study was aimed to determine the antioxidant and anti-ulcer effects of Merremia tridentata root (Arrow-leaf Morning Glory). Antioxidant potential of crude acetone extract and its fractions was evaluated by using various in vitro assays. In the anti-ulcer study, pre-treatment with ethyl acetate fraction (MEF) (50, 100 and 200 mg/kg b.wt.) significantly protected the ethanol-induced gastric ulcer in rats. Simultaneously, the antioxidant enzyme levels of superoxide dismutase, catalase and glutathione in the stomach tissues were significantly increased while pre-treated with MEF. From the results, MEF has the therapeutical potential to prevent gastric ulceration induced by ethanol.

Download File

PDF
Antioxidant and Anti-Ulcer Effects of Ethyl Acetate Fraction of.pdf
Restricted to Repository staff only
Download (1MB)

Additional Metadata

Item Type:	Article
Divisions:	Faculty of Engineering
DOI Number:	https://doi.org/10.1016/j.aaspro.2014.11.057
Publisher:	Elsevier
Keywords:	Antioxidant; Anti-ulcer; Ethanol-induced ulcer; Merremia tridentata; Root
Depositing User:	Nabilah Mustapa
Date Deposited:	01 Dec 2015 04:09
Last Modified:	01 Dec 2015 04:09
Altmetrics:	http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.aaspro.2014.11.057
URI:	http://psasir.upm.edu.my/id/eprint/36491
Statistic Details:	View Download Statistic

Actions (login required)

View Item