UPM Institutional Repository

Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit


Omidizadeh, Alireza and Mohd Yusof, Rokiah and Roohinejad, Shahin and Ismail, Amin and Abu Bakar @ Zakaria, Md Zuki and Bekhit, Alaa El-Din A. (2014) Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit. RSC Advances, 4 (108). pp. 62978-62986. ISSN 2046-2069


This study investigated the anti-insulin resistant activity of red pitaya (Hylocereus polyrhizus) fruit. Fresh pitaya along with two heat-processed pitaya samples with different proportions of phenolic contents, scavenging activities, and soluble dietary fibers were tested in insulin resistant rats over 6 weeks of treatment in a cause-effect study to investigate the anti-insulin resistant components of red pitaya. The results showed that fresh pitaya significantly (p < 0.05) attenuated the insulin resistance, hypertriglyceridemia and atherosclerotic changes induced by fructose supplement in rats. Thermally-treated pitaya at 95 °C for 30 min (containing a low antioxidant content) significantly (p < 0.05) improved hyperinsulinemia. Thermally-treated pitaya at 105 °C for 60 min (containing a low antioxidant and soluble dietary fiber content) fed to rats had no significant effect on insulin resistance, dyslipidemia and atherogenesis. Based on this study, the anti-insulin resistant effect of red pitaya can be attributed to its antioxidant and soluble dietary fiber contents.

Download File

PDF (Abstract)
Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit.pdf

Download (35kB) | Preview

Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Faculty of Veterinary Medicine
DOI Number: https://doi.org/10.1039/C4RA10789F
Publisher: Royal Society of Chemistry
Keywords: Anti-insulin resistant; Hylocereus polyrhizus; Red pitaya
Depositing User: Nabilah Mustapa
Date Deposited: 14 Aug 2015 11:41
Last Modified: 16 Nov 2016 04:49
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1039/C4RA10789F
URI: http://psasir.upm.edu.my/id/eprint/36473
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item