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Antiartherosclerotic effects of plant flavonoids


Salvamani, Shamala and Gunasekaran, Baskaran and Shaharuddin, Noor Azmi and Ahmad, Siti Aqlima and Shukor, Mohd Yunus (2014) Antiartherosclerotic effects of plant flavonoids. BioMed Research International, 2014. art. no. 480258. pp. 1-11. ISSN 2314-6133; ESSN: 2314-6141


Atherosclerosis is the process of hardening and narrowing the arteries. Atherosclerosis is generally associated with cardiovascular diseases such as strokes, heart attacks, and peripheral vascular diseases. Since the usage of the synthetic drug, statins, leads to various side effects, the plants flavonoids with antiartherosclerotic activity gained much attention and were proven to reduce the risk of atherosclerosis in vitro and in vivo based on different animal models. The flavonoids compounds also exhibit lipid lowering effects and anti-inflammatory and antiatherogenic properties. The future development of flavonoids-based drugs is believed to provide significant effects on atherosclerosis and its related diseases. This paper discusses the antiatherosclerotic effects of selected plant flavonoids such as quercetin, kaempferol, myricetin, rutin, naringenin, catechin, fisetin, and gossypetin.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
DOI Number: https://doi.org/10.1155/2014/480258
Publisher: Hindawi Publishing Corporation
Keywords: Atherosclerosis; Flavonoids; Antiartherosclerotic
Depositing User: Nabilah Mustapa
Date Deposited: 15 Dec 2015 03:41
Last Modified: 15 Dec 2015 03:41
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2014/480258
URI: http://psasir.upm.edu.my/id/eprint/36465
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