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A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia


Rafhati, Abdullah Noor and Chee, Keong See and Hoo, Fan Kee and Mohamed Badrulnizam, Long Bidin (2014) A report of three cases of untreated Graves’ disease associated with pancytopenia in Malaysia. Electronic Physician, 6 (3). pp. 877-882. ISSN 2008-5842


Generally, clinical presentations of Graves’ disease range from asymptomatic disease to overt symptomatic hyperthyroidism with heat intolerance, tremor, palpitation, weight loss, and increased appetite. However, atypical presentation of Graves’ disease with hematological system involvement, notably pancytopenia, is distinctly uncommon. Hereby, we present and discuss a series of three untreated cases of Graves’ disease clinically presented with pancytopenia and the hematological abnormalities that responded well to anti-thyroid treatment. With resolution of the thyrotoxic state, the hematological parameters improved simultaneously. Thus, it is crucial that anti-thyroid treatment be considered in patients with Graves’ disease and pancytopenia after a thorough hematological evaluation.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Electronic Physician
Keywords: Graves’ disease; Hyperthyroidism; Thyrotoxicosis; Pancytopenia
Depositing User: Nabilah Mustapa
Date Deposited: 25 Jun 2015 01:21
Last Modified: 29 Oct 2015 06:15
URI: http://psasir.upm.edu.my/id/eprint/36252
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