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Wide distribution of virulence genes among Enterococcus faecium and Enterococcus faecalis clinical isolates


Soheili, Sara and Ghafourian, Sobhan and Sekawi, Zamberi and Neela, Vasantha Kumari and Sadeghifard, Nourkhoda and Ramli, Ramliza and Hamat, Rukman Awang (2014) Wide distribution of virulence genes among Enterococcus faecium and Enterococcus faecalis clinical isolates. The Scientific World Journal, 2014. art. no. 623174. pp. 1-6. ISSN 2356-6140; ESSN: 1537-744X


Enterococcus, a Gram-positive facultative anaerobic cocci belonging to the lactic acid bacteria of the phylum Firmicutes, is known to be able to resist a wide range of hostile conditions such as different pH levels, high concentration of NaCl (6.5%), and the extended temperatures between 5°C and 65°C. Despite being the third most common nosocomial pathogen, our understanding on its virulence factors is still poorly understood. The current study was aimed to determine the prevalence of different virulence genes in Enterococcus faecalis and Enterococcus faecium. For this purpose, 79 clinical isolates of Malaysian enterococci were evaluated for the presence of virulence genes. pilB, fms8, efaAfm, and sgrA genes are prevalent in all clinical isolates. In conclusion, the pathogenicity of E. faecalis and E. faecium could be associated with different virulence factors and these genes are widely distributed among the enterococcal species.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1155/2014/623174
Publisher: Hindawi Publishing Corporation
Keywords: Virulence genes; Enterococcus faecium; Enterococcus faecalis; Clinical isolates
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 15 Feb 2016 01:20
Last Modified: 15 Feb 2016 01:20
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2014/623174
URI: http://psasir.upm.edu.my/id/eprint/36019
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