UPM Institutional Repository

Vitiligo: symptoms, pathogenesis and treatment


Ghafourian, E. and Ghafourian, Sobhan and Sadeghifard, Nourkhoda and Mohebi, Reza and Shokoohini, Y. and Nezamoleslami, S. and Hamat, Rukman Awang (2014) Vitiligo: symptoms, pathogenesis and treatment. International Journal of Immunopathology and Pharmacology, 27 (4). pp. 485-489. ISSN 0394-6320


Vitiligo is an acquired cutaneous disorder of pigmentation, with an incidence of 0.5% to 2% worldwide. There are three major hypotheses for the pathogenesis of vitiligo that are not exclusive of each other: biochemical/cytotoxic, neural and autoimmune. Recent data provide strong evidence supporting an autoimmune pathogenesis of vitiligo. As vitiligo can have a major effect on quality of life, treatment can be considered and should preferably begin early when then disease is active. Current treatment modalities are directed towards stopping progression of the disease and achieving repigmentation. Therapies include corticosteroids, topical immunomodulators, photo(chemo)therapy, surgery, combination therapies and depigmentation of normally pigmented skin. It seems that traditional Chinese medicine could be more effective than the current treatment for vitligo.

Download File

Full text not available from this repository.
Official URL or Download Paper: http://iji.sagepub.com/content/27/4/485.abstract

Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1177/039463201402700403
Publisher: Sage Publications
Keywords: Vitiligo; Chinese medicine; Treatment
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 12 Feb 2016 07:22
Last Modified: 12 Feb 2016 07:22
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1177/039463201402700403
URI: http://psasir.upm.edu.my/id/eprint/35993
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item