Understanding the tabletting characteristics of Ficus deltoidea powder by fitting into compression models

The objective of this paper was to investigate the characteristics of Ficus deltoidea powders during tablet formation using a direct compression method. To understand the data further, compression models were fitted, which included those of Heckel, Kawakita, Adams and Panelli–Filho. F. deltoidea is well-known for its therapeutic properties when used in the form of an extracted powder. We further investigated the effect of the binders Avicel and Acdisol, which are known as a universal binder and a superdisintegrant, respectively. The physical properties, flowability and particle structures were determined to compare behavior and as references to the compression models used. The data were mostly consistent with those predicted by the compression models. As a result, applying compression models, especially the Kawakita model, was successfully performed and can be further related to the development and production of compact F. deltoidea tablets. Thus, this paper provides a fundamental understanding on the tabletting characteristics of F. deltoidea extract powder.

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