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Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital


Citation

Mohd Desa, Mohd Nasir and M. H. , Nurnajwa and Lay, J. and Teoh, J. C. and Amin Nordin, Syafinaz and Mohd Taib, Niazlin (2015) Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital. Sains Malaysiana, 44 (2). pp. 257-260. ISSN 0026-6039

Abstract / Synopsis

A case-control study was conducted based on medical cases of 100 hospitalized patients with Pseudomonas aeruginosa-isolation at a Malaysian hospital. Cases with 50 multidrug-resistant P. aeruginosa MDRPA and 50 non-multidrug-resistant P. aeruginosa (NMDRPA) were randomly included and compared with socio-demographic and clinical data of the patients, using Chi-square and Fisher’s exact tests as the statistical tool. Analysis found no significant association between MDRPA with ages, gender and ethnicity of patients (p>0.050). Other risk factors being investigated were invasive procedure, immunosuppression, bedridden and clinical diagnosis such as central nervous- and respiratory-system disorder, as well as antibiotic exposure during hospitalization and duration of hospital stay with only the last two were found to have significant association (p=0.035 and 0.019, respectively). Some other studies also reported a similar association indicating that the two factors could serve as an important predictive tool for isolation of MDRPA. More studies involving a larger sampling size are warranted to establish the association.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Universiti Kebangsaan Malaysia Press
Keywords: Antibiotic exposure; Hospital stay; Multidrug resistant Pseudomonas aeruginosa; Risk factor
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 31 Dec 2015 04:49
Last Modified: 31 Dec 2015 04:52
URI: http://psasir.upm.edu.my/id/eprint/35281
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