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Preparation of astaxanthin nanodispersions using gelatin-based stabilizer systems


Anarjan, Navideh and Nehdi, Imededdine Arbi and Mohamed Sbihi, Hassen and Al-Resayes, Saud Ibrahim and Malmiri, Hoda Jafarizadeh and Tan, Chin Ping (2014) Preparation of astaxanthin nanodispersions using gelatin-based stabilizer systems. Molecules, 19 (9). pp. 14257-14265. ISSN 1420-3049

Abstract / Synopsis

The incorporation of lipophilic nutrients, such as astaxanthin (a fat soluble carotenoid) in nanodispersion systems can either increase the water solubility, stability and bioavailability or widen their applications in aqueous food and pharmaceutical formulations. In this research, gelatin and its combinations with sucrose oleate as a small molecular emulsifier, sodium caseinate (SC) as a protein and gum Arabic as a polysaccharide were used as stabilizer systems in the formation of astaxanthin nanodispersions via an emulsification-evaporation process. The results indicated that the addition of SC to gelatin in the stabilizer system could increase the chemical stability of astaxanthin nanodispersions significantly, while using a mixture of gelatin and sucrose oleate as a stabilizer led to production of nanodispersions with the smallest particle size (121.4 ± 8.6 nm). It was also shown that a combination of gelatin and gum Arabic could produce optimal astaxanthin nanodispersions in terms of physical stability (minimum polydispersity index (PDI) and maximum zeta-potential). This study demonstrated that the mixture of surface active compounds showed higher emulsifying and stabilizing functionality compared to using them individually in the preparation of astaxanthin nanodispersions.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Food Science and Technology
DOI Number:
Publisher: MDPI
Keywords: Astaxanthin nanodispersions; Emulsifying mixture; Emulsification-evaporation
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 28 Dec 2015 08:45
Last Modified: 28 Dec 2015 08:45
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