Citation
Kura, Aminu Umar and Fakurazi, Sharida and Hussein, Mohd. Zobir and Arulselvan, Palanisamy
(2014)
Nanotechnology in drug delivery: the need for more cell culture based studies in screening.
Chemistry Central Journal, 8 (1).
art. no. 46.
pp. 1-7.
ISSN 1752-153X
Abstract
Advances in biomedical science are leading to upsurge synthesis of nanodelivery systems for drug delivery. The systems were characterized by controlled, targeted and sustained drug delivery ability. Humans are the target of these systems, hence, animals whose systems resembles humans were used to predict outcome. Thus, increasing costs in money and time, plus ethical concerns over animal usage. However, with consideration and planning in experimental conditions, in vitro pharmacological studies of the nanodelivery can mimic the in vivo system. This can function as a simple method to investigate the effect of such materials without endangering animals especially at screening phase.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Medicine and Health Science Institute of Bioscience |
| DOI Number: | https://doi.org/10.1186/1752-153X-8-46 |
| Publisher: | Chemistry Central |
| Keywords: | In vitro; Animal studies; Nanodelivery system; Toxicity; Bio distribution |
| Depositing User: | Nurul Ainie Mokhtar |
| Date Deposited: | 16 Dec 2015 06:55 |
| Last Modified: | 16 Dec 2015 06:55 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1186/1752-153X-8-46 |
| URI: | http://psasir.upm.edu.my/id/eprint/34627 |
| Statistic Details: | View Download Statistic |
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