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Circular antiviral RNA


Citation

Abdul Rahman Omar (2012) Circular antiviral RNA. PI2012001820.

Abstract / Synopsis

The present invention relates to triple helix forming oligonucleotides (TFO) for use in the treatment of diseases mediated by single stranded RNA viruses, for example corona viruses. The invention provides a selection of circular TFO sequences that target different regions of the genome of the virulent Feline coronavirus and that efficiently block the virus’ replication. Thereby the TFO of the present invention provide new means for therapy against viral diseases. The invention relates to the novel TFOs, pharmaceutical compositions comprising the same, the new TFO design and their uses in the treatment of viral diseases.


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Additional Metadata

Item Type: Patent
Application Number: PI2012001820
Filing Date: 2012-04-25
Divisions: Faculty of Veterinary Medicine
Keywords: New antiviral therapeutic; RNA virus; Viral diseases
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 05 Feb 2015 01:07
Last Modified: 02 Sep 2016 06:18
URI: http://psasir.upm.edu.my/id/eprint/33269
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