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Biomarkers in cancer: an overview


Seow, Heng Fong (2008) Biomarkers in cancer: an overview. Malaysian Journal of Medicine and Health Sciences, 4 (1). pp. 23-32. ISSN 1675-8544


Traditional tumour markers such as carcinoembryonic antigen (CEA) that have been used for screening gastrointestinal neoplasia for many years are not specific. However, these markers are useful after diagnosis to monitor progress of the disease and recurrence. New biomarkers are constantly being developed to identify individuals with risk of cancer for early detection, to determine prognosis, to detect recurrence, to predict drug responses and to monitor response to treatment. There are several issues involved in the discovery of biomarkers and their development for clinical applications. This article provides a basic overview of the classes of biomarkers, the current status of molecular profiling and discusses the opportunities as well as challenges ahead to improve biomarker development.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Keywords: Biomarkers; Prognosis; Recurrence; Response to treatment; Risk
Depositing User: Umikalthom Abdullah
Date Deposited: 07 Oct 2015 06:49
Last Modified: 07 Oct 2015 06:49
URI: http://psasir.upm.edu.my/id/eprint/32884
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