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Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM


Citation

Hassan, Hishar and Mustafa, Salasiah and Ahmad Saad, Fathinul Fikri and Nordin, Abdul Jalil (2015) Dose optimisation of 18F-flurodeoxyglucose for whole body PET oncology examination in CDNI of UPM. Pertanika Journal of Science & Technology, 23 (2). pp. 187-192. ISSN 0128-7680; ESSN: 2231-8526

Abstract / Synopsis

A shift to administration of optimal dose of18F-FDG between 4 and 5 MBq/kg from the current practice of higher doses potentially yields a reasonable-to-excellent PET image. For this purpose, whole-body MIP images of 32 patients (23 men, 9 women, age 51.9 ± 13.7 years), administered with 18F-FDG (activity 5.3 ± 0.5 MBq/kg, 45 minutes uptake time) for whole-body PET/CT examinations, were evaluated. Image quality was assessed visually by two radiologists using a three-point scoring scale: poor, reasonable and excellent. The interobserver agreement revealed a kappa value higher than 0.7. Therefore, the utilisation of 18F-FDG dose between 4 and 5MBq/kg is considered an optimum dose for whole-body PET/CT examination.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Universiti Putra Malaysia Press
Keywords: 18F-FDG; Administered dose/body weight (kg); MIP; Optimum dose; PET image quality; PET/CT
Depositing User: Nabilah Mustapa
Date Deposited: 25 Aug 2015 12:18
Last Modified: 26 Jan 2016 12:39
URI: http://psasir.upm.edu.my/id/eprint/32731
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