Citation
Ling Tau Chuan
(2011)
Method for the purification of interferon.
PI2011000150.
Abstract
The present invention discloses a method for the purification of a recombinant microbial Interferon α-2b in an aqueous two-phase system comprising a combination polymer and salt solution. In an embodiment of the present invention, the aqueous two-phase system comprising a combination of polymer and salt solution includes polyethylene glycol (PEG)-potassium phosphate, polyethylene glycol (PEG)-ammonium sulfate, polyethylene glycol (PEG)-sodium carbonate, polyethylene glycol (PEG)-sodium citrate and polyethylene glycol (PEG)-magnesium sulfate. The preferred aqueous two-phase system is the polyethylene glycol (PEG)-potassium phosphate system due to the benefits of low cost and short phase separation time as compared to other systems.
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Additional Metadata
| Item Type: | Patent |
|---|---|
| Application Number: | PI2011000150 |
| Filing Date: | 2011-01-12 |
| Divisions: | Faculty of Engineering |
| Keywords: | Purification; Polyethylene glycol; Interferon. |
| Depositing User: | Suzila Mohamad Kasim |
| Date Deposited: | 04 Sep 2014 04:38 |
| Last Modified: | 04 Sep 2014 04:38 |
| URI: | http://psasir.upm.edu.my/id/eprint/32048 |
| Statistic Details: | View Download Statistic |
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