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Method for the purification of interferon.


Citation

Ling Tau Chuan (2011) Method for the purification of interferon. PI2011000150.

Abstract / Synopsis

The present invention discloses a method for the purification of a recombinant microbial Interferon α-2b in an aqueous two-phase system comprising a combination polymer and salt solution. In an embodiment of the present invention, the aqueous two-phase system comprising a combination of polymer and salt solution includes polyethylene glycol (PEG)-potassium phosphate, polyethylene glycol (PEG)-ammonium sulfate, polyethylene glycol (PEG)-sodium carbonate, polyethylene glycol (PEG)-sodium citrate and polyethylene glycol (PEG)-magnesium sulfate. The preferred aqueous two-phase system is the polyethylene glycol (PEG)-potassium phosphate system due to the benefits of low cost and short phase separation time as compared to other systems.


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Additional Metadata

Item Type: Patent
Application Number: PI2011000150
Filing Date: 2011-01-12
Divisions: Faculty of Engineering
Keywords: Purification; Polyethylene glycol; Interferon.
Depositing User: Suzila Mohamad Kasim
Date Deposited: 04 Sep 2014 04:38
Last Modified: 04 Sep 2014 04:38
URI: http://psasir.upm.edu.my/id/eprint/32048
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