Citation
Bayat, Saadi and Tejo, Bimo Ario and Abd. Malek, Emilia and Mohd Yahaya, Normi and Salleh, Abu Bakar and Abdul Rahman, Mohd Basyaruddin
(2013)
Enantioselectivity investigation of short polar peptides with different positions in the Michael reaction.
Synthetic Communications, 43 (20).
pp. 2725-2732.
ISSN 0039-7911; ESSN: 1532-2432
Abstract
This work reports the effectiveness of short polar peptides as asymmetric catalysts in Michael reactions to attain good yields of enantio- and diastereoselective isomers. In a comparison, glutamic acid and histidine produced greater ee and yields when they were applied as the second amino acid in short trimeric peptides. These short polar peptides were found to be efficient organocatalysts for the asymmetric Michael addition reaction in water.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Biotechnology and Biomolecular Sciences Faculty of Science |
| DOI Number: | https://doi.org/10.1080/00397911.2012.736005 |
| Publisher: | Taylor & Francis |
| Keywords: | Asymmetric; Michael reaction; Organocatalyst; Short polar peptide. |
| Depositing User: | Umikalthom Abdullah |
| Date Deposited: | 20 Oct 2014 07:48 |
| Last Modified: | 24 Aug 2015 07:35 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1080/00397911.2012.736005 |
| URI: | http://psasir.upm.edu.my/id/eprint/30274 |
| Statistic Details: | View Download Statistic |
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