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The effects of probiotics on body weight and biomarkers of animal


Karimi, Golgis and Jamaluddin, Rosita and Parvaneh, Kolsoom (2013) The effects of probiotics on body weight and biomarkers of animal. Pakistan Journal of Nutrition, 12 (8). pp. 793-799. ISSN 1680-5194; ESSN: 1994-7984


Obesity is associated with the alteration of the gut microbiota. In order to determine the effects of probiotics on body weight management and its related biomarkers we performed a systematic review using clinical trial, interventional and experimental studies. We performed a broad search with no date restriction. Primary outcomes were included the parameters related to body weight management. Secondary outcomes were inflammatory markers, lipid profile, blood glucose and insulin level. A total of 12 animal studies were identified. Among these, six studies reported the significant changes in body weight and all the studies had documented significant improvements in at least one body weight related parameter. However, inflammatory markers and lipid profile were significantly improved in the animal model; changes in body weight and energy intake that could be due to probiotics supplementation were controversial. Different strains of gut microbiota have different effects on weight changes. Further studies are needed to identify the role of gut microbiota on weight regulation of human.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.3923/pjn.2013.793.799
Publisher: Asian Network for Scientific Information
Keywords: Gut microbiota; Probiotic; Weight regulation
Depositing User: Raja Norazlinda Raja Azenam
Date Deposited: 27 Dec 2014 07:24
Last Modified: 18 Sep 2015 08:07
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3923/pjn.2013.793.799
URI: http://psasir.upm.edu.my/id/eprint/29809
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