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Using design of experiments methods for assesing peak contact pressure to material properties of soft tissue in human knee


Citation

Bahraminasab, Marjan and Jahan, Ali and Sahari, Barkawi and Arumugam, Manohar and Shamsborhan, Mahmoud and Hassan, Mohd Roshdi (2013) Using design of experiments methods for assesing peak contact pressure to material properties of soft tissue in human knee. Journal of Medical Engineering, 2013. art. no. 891759. pp. 1-11. ISSN 2314-5129; ESSN: 2314-5137

Abstract / Synopsis

Contact pressure in the knee joint is a key element in the mechanisms of knee pain and osteoarthritis. Assessing the contact pressure in tibiofemoral joint is a challenging mechanical problem due to uncertainty in material properties. In this study, a sensitivity analysis of tibiofemoral peak contact pressure to the material properties of the soft tissue was carried out through fractional factorial and Box-Behnken designs. The cartilage was modeled as linear elastic material, and in addition to its elastic modulus, interaction effects of soft tissue material properties were added compared to previous research. The results indicated that elastic modulus of the cartilage is the most effective factor. Interaction effects of axial/radial modulus with elastic modulus of cartilage, circumferential and axial/radial moduli of meniscus were other influential factors. Furthermore this study showed how design of experiment methods can help designers to reduce the number of finite element analyses and to better interpret the results.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Engineering
Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1155/2013/891759
Publisher: Hindawi Publishing Corporation
Keywords: Peak contact pressure; Soft tissue; Human knee; Knee pain; Osteoarthritis
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 18 May 2015 10:39
Last Modified: 25 Aug 2015 14:20
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2013/891759
URI: http://psasir.upm.edu.my/id/eprint/29742
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