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Probiotic effects in allergic disease


Ismail, Intan Hakimah and Licciardi, Paul V. and Tang, Mimi L. K. (2013) Probiotic effects in allergic disease. Journal of Paediatrics and Child Health, 49 (9). pp. 709-715. ISSN 1034-4810; ESSN: 1440-1754


The increasing prevalence of allergic disease has been linked to reduced microbial exposure in early life. Probiotics have recently been advocated for the prevention and treatment of allergic disease. This article summarises recent publications on probiotics in allergic disease, focusing on clinical studies of prevention or treatment of allergic disease. Studies employing the combined administration of pre-natal and post-natal probiotics suggest a role for certain probiotics (alone or with prebiotics) in the prevention of eczema in early childhood, with the pre-natal component of treatment appearing to be important for beneficial effects. On the other hand, current data are insufficient to support the use of probiotics for the treatment of established allergic disease, although recent studies have highlighted new hope in this area. Probiotic bacteria continue to represent the most promising intervention for primary prevention of allergic disease, and well-designed definitive intervention studies should now be a research priority.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1111/jpc.12175
Publisher: Paediatrics and Child Health Division (Royal Australasian College of Physicians)
Keywords: Allergic disease; Immune function; Intestinal microbiota; Prebiotic; Probiotic
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 12 Jul 2016 08:16
Last Modified: 12 Jul 2016 08:16
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1111/jpc.12175
URI: http://psasir.upm.edu.my/id/eprint/29548
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