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Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang


Juanah, Lovetta Yatta and Jalaludin, Juliana and Osman, Malina and Jamil @ Osman, Zubaidah (2013) Seroprevalence of Toxoplasma gondii among schizophrenics at Hospital Kajang. American Journal of Infectious Diseases, 9 (1). pp. 11-16. ISSN 1553-6203; ESSN: 1558-6340


Studies have found a high seroprevalence of T. gondii in schizophrenia patients than controls. This case-control study was done to determine the serprevalence of Toxoplasma gondii and to identify its risk factors among schizophrenia patients at Hospital Kajang. Eighty-eight (88) schizophrenia patients and 88 non-psychiatric controls were examined for the presence of anti-Toxoplasma IgG and IgM antibodies by Enzyme Linked Immunosorbent Assay (ELISA). Questionnaires were used to collect socio-demographic and behavioral data among the respondents. From the results, the seroprevalence of anti-T. gondii IgG antibodies was significantly higher (51.0%) in schizophrenia patients than in controls (30.7%); (OR = 2.01; 95% CI: 2.16-3.01; p = 0.023. There was no significant association between the socio-demographic factors and toxoplasmosis. Beef consumption (p = 0.004, OR = 3.852, CI: 1.550-9.569), pork consumption (p<0.001, OR = 13.089, 95%CI: 4.730-36.219) and risky cat contact (p = 0.047, OR = 4.061, 95% CI: 1.985-16.745), were found to be significantly associated with T. gondii infection. Our results show that there is a relationship between toxoplasmosis and schizophrenia.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.3844/ajidsp.2013.11.16
Publisher: Science Publications
Keywords: Environmental risk factors; Schizophrenia; Seroprevalence; Socio-demographic risk factors; Toxoplasma gondii
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 12 Jul 2016 09:36
Last Modified: 12 Jul 2016 09:36
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3844/ajidsp.2013.11.16
URI: http://psasir.upm.edu.my/id/eprint/29459
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