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Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.


Citation

Malahubban, M. and Alimon, Abdul Razak and Sazili, Awis Qurni and Fakurazi, Sharida and Ab Aziz, Zakry Fitri (2013) Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential. Tropical Biomedicine, 30 (3). pp. 467-480. ISSN 0127-5720

Abstract

Leaves of Andrographis paniculata and Orthosiphon stamineus were extracted with water, ethanol, methanol and chloroform to assess their potential as antibacterial and antioxidant agents. High performance liquid chromatography analysis showed that the methanolic extracts of A. paniculata and O. stamineus leaves gave the highest amounts of andrographolide and rosmarinic acid, respectively. These leaf extracts exhibited antimicrobial and antioxidant activities and, at the highest concentration tested (200 mg/mL), showed greater inhibitory effects against the Gram positive bacteria Bacillus cereus and Staphylococcus aureus than 10% acetic acid. Andrographis paniculata and O. stamineus methanolic and ethanolic leaf extracts also showed the strongest antioxidant activity as compared with the other extracts tested. The bioactive compounds present in these leaf extracts have the potential to be developed into natural antibacterial and antioxidant agents that may have applications in animal and human health.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture
Publisher: Malaysian Society of Parasitology and Tropical Medicine
Keywords: Antibacterial and antioxidant agents; Andrographis paniculata; Poultry; Anti-bacterial properties.
Depositing User: Norhazura Hamzah
Date Deposited: 13 Oct 2014 03:50
Last Modified: 08 Oct 2015 06:50
URI: http://psasir.upm.edu.my/id/eprint/29422
Statistic Details: View Download Statistic

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