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Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.


Citation

Mousavi, Seyed Sadegh and Moeini, Hassan and Mohamad, Rosfarizan and Dinarvand, Mojdeh and Ariff, Arbakariya and Foo, Hooi Ling and Abdul Rahim, Raha (2013) Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250. Research in Biotechnology, 4 (6). pp. 21-29. ISSN 2229-791X

Abstract

The present study was conducted to investigate the effects of culture conditions on folate production by Streptococcus thermophilus BAA-250. Lactose (3g/L) and yeast extract (20g/L) were found to be the more suitable carbon and nitrogen sources for folate production by S. thermophilus BAA-250. para-aminobenzoic acid (pABA) higher than 1 µM had no significant effect on folate biosynthesis. The optimum pH for folate production was shown to be 7.0 with a folate yield and productivity of 54.53 (µg/L) and 2.27 (µg/L.h), respectively. Optimum folate production obtained in the presence of lactose and yeast extract in a controlled pH of 7 during batch fermentation in bioreactor. Kinetic studies indicated that folate production by S. thermophilus is growth-associated process.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
Institute of Bioscience
Keywords: Folate; Lactic acid bacteria; Kinetic model; Streptococcus thermophilus.
Depositing User: Umikalthom Abdullah
Date Deposited: 28 May 2014 11:01
Last Modified: 08 Oct 2015 01:22
URI: http://psasir.upm.edu.my/id/eprint/28123
Statistic Details: View Download Statistic

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