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Characterisation of inhibitory activity of metabolites produced by six strains of Lactobacillus plantarum.


Foo, Hooi Ling and Karunakaramoorthy, Anuradha and Loh, Teck Chwen and Abdul Rahim, Raha and Nor Shamsudin, Mariana and Bejo, Mohd Hair Characterisation of inhibitory activity of metabolites produced by six strains of Lactobacillus plantarum. In: The 7th International Symposium on LAB & Health, 29-31 May 2012, Woci, China. .

Abstract / Synopsis

Antibiotics have been used as therapeutic agents and growth promoters in animal feeds since 1950, However, the excessive use of antibiotics has led to resistance in bacterial pathogens and re-occurrence of eradicated diseases, This situation has urged for the search of an alternative to antibiotics in livestock production, LAB as probiotic is known to produce a wide variety of antibacterial substances; as well as inhibitory metabolites, Therefore, the general objective of this study is to characterize metabolite produced by six strains of locally isolated Lactobacillus plantarum, The results of stability test showed that metabolites were able to tolerate a wide range of pH, stable at moderate temperature but able to retain activity at different storage temperatures. Inhibitory test was conducted by agar well diffusion assay on selected aquaculture pathogens for 63 combinations of metabolites subsequently (1; UL4, 2; TL1, 3; RI11,4; RG14, 5; RS5 and 6; RG11). Based on total scores, the best combinations were 12456, 123456, 12356 and 23456, The versatile characteristics of the studied metabolites reveal the potential of their application in livestock, aquaculture and food industries respectively.

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Additional Metadata

Item Type: Conference or Workshop Item (Paper)
Divisions: Faculty of Agriculture
Faculty of Biotechnology and Biomolecular Sciences
Faculty of Medicine and Health Science
Faculty of Veterinary Medicine
Institute of Bioscience
Institute of Tropical Agriculture
Notes: Full text are available at Special Collection Division Office
Keywords: Characterisation; Metabolites; Lactobacillus planatarum; Stability; Inhibitory activity.
Depositing User: Samsida Samsudin
Date Deposited: 10 Feb 2014 09:43
Last Modified: 11 Apr 2014 11:36
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