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Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats


Citation

Abu Hassim, Hasliza and Mohamed Mustapha, Noordin and Goh, Yong Meng (2011) Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats. Pertanika Journal of Tropical Agricultural Science, 34 (1). pp. 151-155. ISSN 1511-3701; ESSN: 2231-8542

Abstract / Synopsis

The efficacy of exercise and dietary polyunsaturated fatty acid (PUFA) on streptozotocin-induced diabetes in rats was investigated based on blood lipid profiles, with respect to triglycerides, total cholesterol, high-density lipoprotein (HDL)-cholesterol, and low-density lipoprotein (LDL)-cholesterol. A total of 32 Sprague-Dawley male rats were used and divided into eight groups. Four groups were exercised daily for 8 weeks, while the other four were sedentary. Treatment diets were defined as follows: rat chow diet only (Control diet), rat chow added with 2:1, menhaden oil:soybean oil (Diet 1), rat chow added with 1:2, menhaden oil:soybean oil (Diet 2), and rat chow added with 10% (w/w) butter (Diet 3). Blood plasma was collected at the end of 8 weeks for blood lipid profiles determination. The results showed that a combination of exercise and dietary PUFA significantly improved lipid abnormalities by lowering the triglycerides, total cholesterol, and LDL-cholesterol levels.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Veterinary Medicine
Publisher: Universiti Putra Malaysia Press
Keywords: Blood lipids; Exercise; Diabetes; Polyunsaturated fatty acids; Rat
Depositing User: Nur Farahin Ramli
Date Deposited: 22 Nov 2013 03:06
Last Modified: 21 Nov 2016 07:32
URI: http://psasir.upm.edu.my/id/eprint/25430
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