Alpha-mangostin and beta-mangostin from Cratoxylum laucum.

Citation

Ee, Gwendoline Cheng Lian and Md.Sukari, Mohd. Aspollah and Wei , Chung Sim (2011) Alpha-mangostin and beta-mangostin from Cratoxylum laucum. Research Journal of Chemistry and Environment, 15 (2). pp. 62-66. ISSN 0972-0626

Abstract

Our continuing interest in xanthones and anthraquinones from the Cratoxylum genus has led us to look at Cratoxylum glaucum. This resulted in the isolation of alpha-mangostin (1), beta-mangostin (2), fuscaxanthone C (3), 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone (4), beta-sitosterol (5), 1,8-dihydroxy-3-methoxy-6-methylanthraquinone (6), stigmasterol (7), friedelin (8) and betulinic acid (9). Structural elucidations of these compounds were achieved by using ID and 2D NMR spectroscopic experiments. Cytotoxic assays indicated that the hexane and ethyl acetate extracts demonstrated cytotoxicity against the MCF7 cancer cell line. Meanwhile, the ethyl acetate and methanol extracts of C. glaucum inhibited the HL-60 cancer cell line activity.

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Additional Metadata

Item Type:	Article
Divisions:	Faculty of Science
Publisher:	International Congress of Chemistry and Environment
Keywords:	Mangostin; Cratoxylum laucum.
Depositing User:	Nur Farahin Ramli
Date Deposited:	23 Aug 2013 03:00
Last Modified:	09 Sep 2015 04:54
URI:	http://psasir.upm.edu.my/id/eprint/24896
Statistic Details:	View Download Statistic

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