UPM Institutional Repository

Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.


Citation

Roohinejad, Shahin and Omidizadeh, Alireza and Mirhosseini, Hamed and Saari, Nazamid and Mustafa, Shuhaimi and Mohd Yusof, Rokiah and Hussin, Anis Shobirin and Abdul Hamid, Azizah and Abd. Manap, Mohd. Yazid (2010) Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats. Journal of the Science of Food and Agriculture, 90 (2). pp. 245-251. ISSN 0022-5142, ESSN:1097-0010

Abstract

Background: Brown rice is unpolished rice with immeasurable benefits for human health. Brown rice (BR) and pre-germinated brown rice (PGBR) are known to contain various functional compounds such as gamma-oryzanol, dietary fibre and gamma-aminobutyric acid (GABA). In the present study, the experimental diets containing BR and PGBR (24, 48 h pre-germination) were used to investigate the influence of pre-germination time of brown rice on blood cholesterol in Sprague-Dawley male rats. Result: Hypercholesterolaemia and elevation of LDL-cholesterol were successfully ameliorated by the experimental diets containing BR and PGBR (24 and 48 h pre-germination). As compared to the control sample, the pre-germination time had a significant (P < 0.05) effect on blood cholesterol of Sprague-Dawley male rats. It was also found that the significantly (P < 0.05) better effect on lipid profile of hypercholesterolaemic rats was observed by prolonging the pre-germination time. As compared to non-germinated brown rice, the germinated brown rice showed the higher cardio-protective effect on hypercholesterolaemic Sprague-Dawley male rats. Conclusion: The present study suggests that the changes of blood cholesterol can be mainly modulated by using the PGBR rather than BR. The prolonging of pre-germination time led to an increase in the bioactive components, thereby providing a more efficient functional diet affecting the high blood cholesterol. This study suggests that PGBR can be used instead of BR and polished rice in the human diet.


Download File

[img]
Preview
PDF (Abstract)
Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats..pdf

Download (182kB) | Preview
Official URL: http://www.wiley.com/

Additional Metadata

Item Type: Article
Divisions: Faculty of Food Science and Technology
DOI Number: https://doi.org/10.1002/jsfa.3803
Publisher: Wiley-Blackwell
Keywords: γ-amino butyric acid (GABA); γ-oryzanol; Brown rice; Dietary fibre; Hypercholesterolaemia; Pre-germination.
Depositing User: Nur Farahin Ramli
Date Deposited: 04 Dec 2013 02:47
Last Modified: 02 Nov 2015 02:43
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1002/jsfa.3803
URI: http://psasir.upm.edu.my/id/eprint/24036
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item