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A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals


Teo, Brian Sheng Xian and Basri, Mahiran and Zakaria, Mohd Rezuwan Shah and Salleh, Abu Bakar and Raja Abdul Rahman, Raja Noor Zaliha and Abdul Rahman, Mohd Basyaruddin (2010) A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals. Journal of Nanobiotechnology, 8. art. no. 4. pp. 1-11. ISSN 1477-3155


Background:Cosmeceuticals are cosmetic-pharmaceutical hybrids intended to enhance health and beauty of the skin. Nanocosmeceuticals use nano-sized system for the delivery of active ingredients to the targeted cells for better penetration. In this work, nanoemulsion from palm oil esters was developed as a delivery system to produce nanocosmeceuticals. The stability of the resulting formulation was tested using various methods. In addition, the effect of components i.e. Vitamin E and Pluronic F-68 on the formulation was also studied. Results: Both vitamin E and Pluronic F-68 were found to co-emulsify and co-stabilized the formulations. The best formulation was found to be the one having the composition of 10% Palm Oil Esters (POEs), 10% vitamin E, 24% Tween 80, 2.4% Pluronic F-68 and 53.6% deionised water. Those compositions are considered to be the best as a nanocosmeceutical product due to the small particle size (94.21 nm), low occurrence of Ostwald ripening and stable at different storing temperatures (5, 25 and 45°C) for four weeks. Conclusions:Palm oil esters-in-water nanoemulsions loaded with vitamin E was successfully formulated and has the potential for the use as nanocosmeceuticals.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
Faculty of Science
DOI Number: https://doi.org/10.1186/1477-3155-8-4
Publisher: BioMed Central
Keywords: Nanobiotechnology; Bio materials; Cosmeceuticals; Nanocosmeceuticals
Depositing User: Najwani Amir Sariffudin
Date Deposited: 09 Jul 2014 04:40
Last Modified: 26 Sep 2016 07:53
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1186/1477-3155-8-4
URI: http://psasir.upm.edu.my/id/eprint/22294
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