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Development of Bioaffinity Chromatography for Uricase Purification


Salleh, Abu Bakar (1980) Development of Bioaffinity Chromatography for Uricase Purification. Pertanika, 3 (2). pp. 97-102.


The uricase inhibitors urate, xanthine, oxonate and cyanurate were tried as ligands, for preparing bioaffinity support for chromatographic separation of uricase. Only derivatised purines showed inhibitory properties, whereas derivatised s-triazines seemed to lose their absorptive capacity. Chromatographic separation on a bioaffinity support produced higher yield and better purification of Uricase than conventional chromatographic technique.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Environmental Studies
Keywords: uricase, affinity chromatography
Depositing User: Nur Izyan Mohd Zaki
Date Deposited: 10 Nov 2009 00:19
Last Modified: 27 May 2013 06:58
URI: http://psasir.upm.edu.my/id/eprint/2056
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