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The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice.


Citation

Jaafar, Rohana and Abdullah Mahdy, Zaleha and Siraj, Harlina Halizah and Khaza'ai , Huzwah and Abd Mutalib, Mohd Sokhini and Mohd Dali, Ahmad Zailani Hatta (2010) The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice. Journal of Neonatal-Perinatal Medicine, 3 (3). pp. 217-221. ISSN 1934-5798, EISSN: 1878-4429

Abstract

Objective: To determine the effect of maternal antenatal vitamin E supplementation on neonatal jaundice. Methods: A randomized double blind controlled trial assessing the role of vitamin E in the prevention of preeclampsia was conducted in a tertiary hospital over two years. From 12-16 weeks gestation until delivery, primigravida mothers with singleton pregnancies received either 100 mg daily vitamin E in the form of tocotrienol rich fraction, or placebo. The newborns were assessed for jaundice. Results: Among 262 infants, 136 were in the vitamin E group and 126 in the placebo group. The incidence of neonatal jaundice was similar: 38% (54/136) in the vitamin E group and 36% (45/126) in the placebo group (p= 0.10). Nevertheless, the vitamin E group had a tendency for lower peak serum bilirubin, although not significantly so. Conclusion: Maternal antenatal vitamin E supplementation had no effect on the incidence of neonatal jaundice.


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Additional Metadata

Item Type: Article
Subject: Jaundice, Neonatal.
Subject: Vitamin E.
Subject: Newborn infants - Diseases.
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.3233/NPM-2010-0118
Publisher: IOS Press
Keywords: Antenatal; Jaundice; Neonatal; Vitamin E
Depositing User: Raja Norazlinda Raja Azenam
Date Deposited: 19 Feb 2013 05:06
Last Modified: 08 Oct 2015 08:12
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3233/NPM-2010-0118
URI: http://psasir.upm.edu.my/id/eprint/17313
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