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Secretome of Staphylococcus aureus


Liew, Yun Khoon and Neela, Vasantha Kumari (2010) Secretome of Staphylococcus aureus. African Journal of Microbiology Research, 4 (7). art. no. 473E2AC12148. pp. 500-508. ISSN 1996-0808


Presence of secreted proteins is the key for sustenance of Staphylococcus aureus strains in the host system. General secretory (Sec) system is a well known and major secretion system that is responsible for the transportation of exoproteins across the bacterial cytoplasmic membrane and cell wall. In order to define the secretome of S. aureus, the availability of combination of two-dimensional gel electrophoresis (2-DE) with the latest advanced techniques (MALDI-TOF and ESI-MS/MS) has provided a powerful tool for the investigation of a large number of protein spots with the aim of identifying new drug candidates and discovering new diagnostics tools. In this paper, we present a short review regarding S. aureus general secretory system and role of secreted protein in host cells, and discuss the proteomic, together with genomics of S. aureus.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Academic Journals
Keywords: Staphylococcus aureus; Secretome; General secretory system; Pathogenesis; Proteomic
Depositing User: Raja Norazlinda Raja Azenam
Date Deposited: 14 May 2013 06:59
Last Modified: 20 Nov 2017 02:34
URI: http://psasir.upm.edu.my/id/eprint/16637
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