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PET image reconstruction incorporating 3D mean-median sinogram filtering


Mokri, Siti Salasiah and Saripan, M. Iqbal and Abd. Rahni, Ashrani Aizzuddin and Nordin, Abdul Jalil and Hashim, Suhairul and Marhaban, Mohammad Hamiruce (2016) PET image reconstruction incorporating 3D mean-median sinogram filtering. IEEE Transactions on Nuclear Science, 63 (1). pp. 157-169. ISSN 0018-9499


Positron Emission Tomography (PET) projection data or sinogram contained poor statistics and randomness that produced noisy PET images. In order to improve the PET image, we proposed an implementation of pre-reconstruction sinogram filtering based on 3D mean-median filter. The proposed filter is designed based on three aims; to minimise angular blurring artifacts, to smooth flat region and to preserve the edges in the reconstructed PET image. The performance of the pre-reconstruction sinogram filter prior to three established reconstruction methods namely filtered-backprojection (FBP), Maximum likelihood expectation maximization-Ordered Subset (OSEM) and OSEM with median root prior (OSEM-MRP) is investigated using simulated NCAT phantom PET sinogram as generated by the PET Analytical Simulator (ASIM). The improvement on the quality of the reconstructed images with and without sinogram filtering is assessed according to visual as well as quantitative evaluation based on global signal to noise ratio (SNR), local SNR, contrast to noise ratio (CNR) and edge preservation capability. Further analysis on the achieved improvement is also carried out specific to iterative OSEM and OSEM-MRP reconstruction methods with and without pre-reconstruction filtering in terms of contrast recovery curve (CRC) versus noise trade off, normalised mean square error versus iteration, local CNR versus iteration and lesion detectability. Overall, satisfactory results are obtained from both visual and quantitative evaluations.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Engineering
Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1109/TNS.2015.2513484
Publisher: Institute of Electrical and Electronics Engineers
Keywords: Filtered-backprojection; Maximum likelihood expectation maximization OSEM; Mean and median filters; Median root prior; PET sinogram
Depositing User: Nabilah Mustapa
Date Deposited: 08 Jun 2016 01:53
Last Modified: 08 Jun 2016 01:53
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1109/TNS.2015.2513484
URI: http://psasir.upm.edu.my/id/eprint/16431
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