Citation
Muniandy, Sithi V. and Stanslas, Johnson
(2008)
Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.
Computerized Medical Imaging and Graphics , 32 (7).
pp. 631-637.
ISSN 0895-6111; ESSN:1879-0771
Abstract
Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. The gray-level images of nuclear chromatin are modelled as random fields. We used two-dimensional isotropic generalized Cauchy field to characterize local self-similarity and global long-range dependence behaviors in the image spatial data. Generalized Cauchy field allows the description of fractal behavior inferred from fractal dimension and the long-range dependence inferred from correlation exponent to be carried out independently. We demonstrated the usefulness of locally self-similar random fields with long-range dependence for modelling chromatin condensation.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Medicine and Health Science |
| DOI Number: | https://doi.org/10.1016/j.compmedimag.2008.07.003 |
| Publisher: | Elsevier |
| Keywords: | Apoptosis; Fractal dimension; Locally self-similar processes; Long-range dependence; Morphology. |
| Depositing User: | Raja Norazlinda Raja Azenam |
| Date Deposited: | 04 Jul 2013 00:17 |
| Last Modified: | 23 Oct 2015 06:27 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.compmedimag.2008.07.003 |
| URI: | http://psasir.upm.edu.my/id/eprint/15672 |
| Statistic Details: | View Download Statistic |
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