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Cis-clerodane-type furanoditerpenoids from Tinospora crispa


Choudhary, Muhammad Iqbal and Muhammad Ismail, and Shaari, Khozirah and Ahmed Abbaskhan, and A. Sattar, Samina and Lajis, Md. Nordin and Atta-ur-Rahman, (2010) Cis-clerodane-type furanoditerpenoids from Tinospora crispa. Journal of Natural Products, 73 (4). pp. 541-547. ISSN 0163-3864; ISSN: 1520-6025


Phytochemical and cytotoxicity investigations on organic solvent extracts of the aerial parts of Tinospora crispa have led to the isolation of 15 cis-clerodane-type furanoditerpenoids. Of these, nine compounds (1-9) were found to be new. Spectroscopic assignments of a previously reported compound, borapetoside A (13), were revised on the basis of HMQC and HMBC correlations. No discernible activity was observed when compounds 10-13 were subjected to evaluation in cytotoxicity assays against human prostate cancer (PC-3) and the normal mouse fibroblast (3T3) cell lines.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
DOI Number: https://doi.org/10.1021/np900551u.
Publisher: American Chemical Society
Keywords: Cis-clerodane-type furanoditerpenoids; Tinospora crispa; Phytochemical; Cytotoxicity
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 31 Jul 2015 03:32
Last Modified: 02 Nov 2015 03:54
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1021/np900551u.
URI: http://psasir.upm.edu.my/id/eprint/13597
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